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Evidence answer · Bones

Can statins (cholesterol-lowering medications) affect your bones?

Uncertain · Insufficient evidence

The available study contains no data on bones, so no answer can be given on the basis of this material. If you have concerns about your bone health while using statins, discuss them with your doctor.

The full answer

The only study provided (IMPROVE-IT) examined what happens when you add ezetimibe, a cholesterol-lowering drug, to statin therapy in people who had suffered a heart attack or severe angina. That study looked exclusively at cardiovascular outcomes, such as new heart attacks and mortality. Bone density, fractures, or any other bone-related outcomes were not measured or reported in it.

On the basis of this source, it is simply not possible to say anything about the effect of statins on your bones. The question therefore cannot be answered: the required evidence is not contained in the available study.

The evidence
1 studies

The only source provided (PMID 26039521) contains no bone-related outcomes whatsoever. The question cannot be answered on the basis of this material.

Last reviewed: July 2026
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