GLP-1
GLP-1 (glucagon-like peptide-1) is a gut hormone that stimulates insulin release, curbs appetite and slows stomach emptying. Medicines that mimic it, such as semaglutide and tirzepatide, are used for diabetes and obesity.
GLP-1 at a glance
For whom
People with overweight or obesity, and people with type 2 diabetes, by prescription and under a doctor supervision.
Not for whom
Not meant for cosmetic weight loss without a medical reason. Be cautious with severe gastrointestinal problems or a history of pancreatitis; consult your doctor.
Usual dose
Weekly injection (semaglutide, tirzepatide) or a daily pill, at an increasing dose. Always by prescription.
Key caveats
Works while you take it; weight often returns after stopping. Side effects are mainly nausea and gut complaints. Combine with diet and exercise to preserve muscle mass.