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Supplement use shifted dramatically over fifty years

Fifty years ago, a vitamin pill was something unusual. Today, millions of Americans take multiple supplements every day.

LongevityWatch editorsJune 17, 2026

An analysis published via STAT News examines how dietary supplement use in the United States transformed over recent decades. The article covers shifts in the popularity of specific supplements, demographic patterns, and the role of marketing and legislation in sector growth.

In the early 1990s, regulation in the US took a critical turn. The Dietary Supplement Health and Education Act of 1994 made it significantly easier for manufacturers to bring supplements to market without providing advance proof of efficacy. That triggered explosive growth in both supply and consumption. At the same time, consumer motivation shifted: from correcting deficiencies toward actively pursuing health gains or slowing aging.

What the data show

Multivitamin use was dominant for decades but has declined in relative terms in recent years. Use of specific supplements grew strongly: vitamin D, omega-3 fatty acids, magnesium, and, more recently, nicotinamide riboside (NR) and other NAD+ precursors. That shift partly reflects broader trends in medical science, and partly growing consumer awareness of aging research.

What do we know about effectiveness?

Growth in use does not always track with the available evidence. For some supplements, such as vitamin D in people with a confirmed deficiency, the evidence base is reasonably solid. For many others, including popular longevity supplements, evidence remains limited to animal models or small human studies. The gap between scientific evidence and consumer behavior is a recurring theme in the field.

For LongevityWatch readers, the broader lesson is relevant: the popularity of a supplement is not a measure of its effectiveness. At the same time, the growth of the sector signals increasing public interest in preventive health and aging interventions.

Read the original article

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