Do you age faster if you have chronic pain?
Chronic pain is linked to faster biological ageing, primarily through reduced physical activity and the side effects of medications. If you have long-term pain, it is worth working with your doctor to find ways to stay active nonetheless.
Chronic pain is associated with a faster ageing process, but the pain itself is probably not the only cause. Persistent pain has been linked to a higher risk of premature death and accelerated cognitive decline in older adults. Whether pain causes this directly, or whether underlying disease processes play a role in both the pain and the ageing, has not yet been clarified.
The clearest mechanism runs through physical movement. Chronic pain discourages physical activity, and inactivity is one of the strongest drivers of biological ageing. People who move less because of pain age physiologically faster. This relationship is reasonably well supported and likely explains a large part of the effect.
The medications prescribed for chronic pain can also have adverse consequences. Commonly used painkillers in older adults increase the risk of falls, temporary memory problems, constipation and urinary problems. These side effects are themselves harmful to long-term health.
Research is being conducted into whether certain compounds can reduce pain and inflammation and thereby indirectly slow ageing, but that research remains exclusively at the laboratory stage. There is no clinical evidence that anything of the kind works in humans.
Based on a review by the National Institute on Aging (PMID 31004724) and a study on inactivity as a driver of ageing (PMID 23798298). All associations are observational or probably causal; no RCTs are available demonstrating that pain treatment slows biological ageing.