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What actually helps with chronic low back pain?

Moderate evidence

Strength and stabilisation exercises have the strongest evidence base for chronic low back pain; if the effect is insufficient, anti-inflammatory drugs are the first pharmacological step, but opioids and surgery can almost always be avoided.

Strength and stabilisation exercises (such as core training) are the most effective approach for chronic low back pain. They outperform other forms of exercise, including cardiovascular training. Exercise therapy in general reduces pain by an average of about 7 to 13 points on a scale of 100, and improves daily functioning. That is a modest but demonstrated effect, consistent across multiple meta-analyses.

Rest does not work, even though it used to be the standard advice. Inactivity does not improve chronic pain. Exercise is safer than it sounds: temporary muscle soreness in the first few weeks is the most commonly reported side effect, but there are no serious risks.

Beyond exercises, there are more non-pharmacological options that the American College of Physicians guideline recommends as first choice: multidisciplinary rehabilitation, cognitive behavioural therapy, mindfulness, yoga, tai chi and acupuncture. The evidence for these varies in quality, but they are explicitly placed above medication as a starting point. A newer approach, Cognitive Functional Therapy (a combination of behavioural psychology and tailored physiotherapy), also shows positive signals, but has so far only been studied in smaller trials.

If none of that works, anti-inflammatory drugs such as ibuprofen are the first pharmacological choice. Tramadol and duloxetine come after that. Opioids are at the bottom of the list: they are only appropriate when everything else has failed, because of the risk of addiction and other side effects.

What you are better off avoiding: ordering an MRI or X-ray purely out of habit, spinal injections and back surgery are used far more often worldwide than the evidence justifies. For chronic low back pain they generally offer no greater benefit, and they increase the risk that symptoms will become entrenched.

The evidence
6 studies · 4 meta-analyses

Three meta-analyses on exercise therapy (PMID 16034851, 25681408, 28436583), one guideline from the American College of Physicians (PMID 28192789), one population-level review on overtreatment (PMID 29573872) and one limited abstract on Cognitive Functional Therapy (PMID 29669082). The strength of evidence varies by treatment.

Last checked: August 2026 · how this was judged
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