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Does the country you live in affect your biological age?

Where you live and how much money you have is strongly associated with how quickly you age biologically; the largest gap between biological and calendar age is found in low-income countries. This is one large study, but with nearly 162,000 participants and consistent effects across 40 countries, the findings deserve to be taken seriously.

Yes, it makes a considerable difference. A study of nearly 162,000 people from 40 countries found that people in Europe age most favourably on average: their biological age lags least behind their calendar age. The gap was largest in Egypt and South Africa, where the body aged biologically at a significantly faster rate than the calendar would suggest. Asian and Latin American countries fell in between. There were also differences within Europe: eastern and southern Europe scored worse than the rest.

Which factors explain this? Lower income was the strongest predictor of accelerated biological ageing: people with less money aged faster, and this held true at both the individual and regional level. The association was medium to large in magnitude. Poor air quality and sociopolitical circumstances, such as high inequality, limited political freedoms and gender inequality, were also associated with faster ageing.

The consequences are concrete. People who age biologically faster had, at follow-up measurements, a greater likelihood of cognitive decline and loss of daily functioning. The functional difference was the largest: the association had a medium to large effect size.

An important caveat: the study is observational. This means that country or income have not been proven to cause ageing, but they are strongly associated with it. People who move from a poor country to a wealthy one, for example, also bring part of their biological clock with them. Nevertheless, the researchers point to a 'likely causal' interpretation, given the breadth and consistency of the findings.

The evidence
1 study · ≈ 161,981 participants

All findings come from a single large cross-sectional and longitudinal study (PMID 40659767, n=161,981, 40 countries). The effect sizes are robust and statistically sound, but independent replication is still lacking.

Last checked: September 2026 · how this was judged
Related answers

How large can the difference between my chronological age and my biological age be?

The typical spread between your biological and calendar age is around one to two years. Studies mention no hard upper limit, but biological age does predict health risks better than your year of birth.

Which lifestyle factors influence your biological age the most?

Sitting for prolonged periods, a disrupted circadian rhythm and muscle loss are the best-supported negative factors for your biological age; exercising regularly and maintaining a consistent sleep-wake rhythm are the most concrete steps you can take right now.

Moderate evidence

How can I measure my biological age?

Epigenetic clocks, in particular GrimAge and PhenoAge, currently offer the best estimate of your biological age, but they are not yet ready for straightforward home use and require expert interpretation.

Moderate evidence

What does smoking do to your biological age?

Smoking measurably accelerates the biological ageing of lung cells, the immune system and the reproductive system. Quitting smoking reverses part of that damage, in some cases even completely after ten years.

Can you really lower your biological age, and does the research support this?

There are promising indications that biological age is measurable and perhaps controllable, but clinical evidence that you can truly and lastingly lower that age is still lacking. Wait for larger studies before basing major decisions on this.

Preliminary evidence

Can you see your biological age in your blood pressure?

Your blood pressure, and especially your nighttime blood pressure, says something about how your blood vessels are ageing, but it is not a complete measure of biological age. A 24-hour measurement provides more information than a single doctor's appointment, and with the DASH diet you can actively improve your values.

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