longevitywatch

Aging clocks

Biological age, epigenetic clocks and biomarkers of aging.

65 answers, from 427 studies
Last updated: September 2026
Key questions
Does alpha-ketoglutarate work against ageing?
In animal research AKG clearly extends lifespan, but solid evidence in humans is still lacking. Wait for the results of the…
Preliminary evidence
What can you expect from a longevity clinic in the Netherlands?
A longevity clinic can offer you an interesting biomarker measurement and a good exercise programme, but for most supplements…
Preliminary evidence
Does your telomere length tell you anything useful about your health?
Telomere length is a relevant biological measure, but does not give a clear-cut signal: shorter telomeres increase the risk of…
Moderate evidence
Do epigenetic clocks differ so much that your result is essentially random?
Different epigenetic clocks sometimes lead to opposing conclusions, so your result does not necessarily say anything absolute.…
Moderate evidence
Can epigenetic reprogramming reverse ageing?
Epigenetic reprogramming consistently and convincingly rejuvenates cells and tissues in animal and laboratory research, but no…
Preliminary evidence
What does your klotho level tell you about how fast you are ageing?
Your klotho level demonstrably declines with age and is associated with greater disease risk, but whether measuring it is…
Moderate evidence
What do we know about rapamycin as an anti-ageing agent in humans?
Rapamycin shows early positive signals in humans for immune function and skin, but long-term safety is unknown and side…
Preliminary evidence
Does plasma exchange (plasmapheresis) work against ageing?
There are initial, cautiously positive indications from one small study, but it is too small and too influenced by commercial…
Preliminary evidence
Latest articles
11 Sep
Longevity science is losing the public messaging battle
Cardiology spent decades teaching the public what blood pressure and cholesterol numbers mean.
2 min
10 Sep
Blood test may detect cervical cancer recurrence earlier
After treatment for cervical cancer, the key question is whether the disease will return. A blood test based on freely…
1 min
10 Sep
Genes and metabolism shift in measurable aging patterns
What does human aging actually look like, measured from the inside?
1 min
10 Sep
Measuring biological age: which tests actually mean something, and which don't
Epigenetic clocks, saliva tests, blood chemistry: which measure of your biological age is reliable, what can your doctor offer…
3 min
07 Sep
What aging clocks can learn from clinical trials
Biological aging clocks are among the most discussed tools in longevity science. But how well do they perform as measuring…
2 min
04 Sep
A blood test detects Alzheimer’s seeds early
Alzheimer’s doesn’t start with forgetting. It starts with a microscopic cluster of misfolded protein in your blood, years…
1 min
04 Sep
Dogs may hold clues to human aging
Dogs live only a fraction of a human lifespan, but they appear to age in remarkably similar ways.
1 min
02 Sep
Tissue scans reveal each organ ages differently
Not every organ ages at the same pace. A new framework scans tissue images from dozens of organs and measures biological age…
2 min
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