longevitywatch

Interventions

Rapamycin, metformin, GLP-1 and other widely-discussed compounds.

255 answers, from 1,621 studies
Last updated: July 2026
Key questions
How much berberine do you need per day?
The best-supported doses range between 0.6 and 1 gram per day, depending on your goal. If you use metformin, discuss berberine…
Moderate evidence
How much probiotic do you need per day?
There is no universal daily dose for probiotics: how much you need depends strongly on the bacterial strain, the application,…
Moderate evidence
How much ashwagandha do you need per day?
For stress reduction, 240 to 500 mg per day already appears to have an effect; for safety, 600 mg per day has been studied for…
Yes · Moderate evidence
How much CoQ10 do you need per day?
There is no officially established daily dose of CoQ10 for healthy people. If you are considering supplementation, discuss it…
Insufficient evidence
How much iron do you need per day?
For healthy adults without a deficiency, compensating for 1 to 2 mg of iron per day through a varied diet is sufficient; if…
Yes · Moderate evidence
What do we really know about metformin and ageing?
Metformin may extend healthy years by helping to prevent disease, but whether it also slows ageing itself in healthy people…
Preliminary evidence
Can probiotics improve your health in later life?
Clinical studies into probiotics and ageing are ongoing, but results are not yet available. At this point there is too little…
Insufficient evidence
What can help women increase their libido?
There are several well-supported options depending on your life stage: for women after menopause, transdermal testosterone has…
Yes · Moderate evidence
Latest articles
27 Jul
FDA panel greenlights five peptides for compounding pharmacies
Five peptides are on the verge of becoming available through regulated pharmacies in the United States.
1 min
27 Jul
Mini brains predict who benefits from Alzheimer’s treatment
Not every Alzheimer’s patient responds to treatment the same way. That has long been known, but there was no reliable method…
1 min
25 Jul
Tau-targeting drugs gain fresh momentum in Alzheimer’s
For years, Alzheimer’s research focused on amyloid, a protein that clumps in the brain.
1 min
24 Jul
FDA panel backs legal access to four longevity peptides
Four substances popular in the longevity world but not officially approved may soon be available through compounding…
1 min
19 Jul
Ozempic slows biological ageing markers in people with HIV
Semaglutide, the active ingredient in Ozempic and Wegovy, appears to slow biological ageing markers in adults with HIV. This…
1 min
19 Jul
Drug for spinal injury repairs DNA in Alzheimer brains
A drug originally developed for spinal cord injury appears to do something no approved Alzheimer’s treatment has managed:…
1 min
18 Jul
Targeting senescent cells cuts post-chemo inflammation
Chemotherapy saves lives but accelerates biological ageing in the body.
1 min
17 Jul
Cancer signal both feeds tumors and boosts immunity
A signaling pathway that helps breast cancer grow also strengthens the immune response against the tumor. That paradoxical…
1 min
Related topics
Newsletter

Stay in the loop

Twice a week, the most important longevity research in your inbox.