Does methylene blue really work for your energy and brain?
Do not take this as a supplement. Methylene blue is a registered medicine and industrial dye, not a food, and not authorised as an EU supplement. For energy or brain function in healthy people there is no evidence, and it can be dangerous: it interacts severely with antidepressants (serotonin syndrome) and is risky with a G6PD deficiency.
Methylene blue is promoted online as a substance for energy and brain function, but that is not based on evidence in healthy people. It is a medicine (among other things for a blood disorder) and an industrial dye, not a nutrient.
As a supplement it is not authorised in the EU. And it is not harmless: methylene blue inhibits the enzyme MAO-A, so that together with antidepressants such as SSRIs it can cause a life-threatening serotonin syndrome, a risk regulators explicitly warn about.
It is also dangerous for people with a G6PD deficiency (it can cause breakdown of red blood cells) and its industrial origin can bring impurities. In short: do not take it yourself; only use it if a doctor prescribes it as a medicine.
Based on the medicine and novel-food status and safety warnings (among others about serotonin syndrome); no evidence for energy or brain in healthy people.
How healthy are blueberries and other red/blue fruits for your brain?
Eating blueberries daily has a modest but consistent positive effect on memory and vascular health, particularly if you are already noticing mild cognitive decline. For healthy people without complaints the benefit is less certain, but the risk is negligible and the chance of benefit is real.
Does lion's mane really work for your brain?
Lion's mane shows cautiously positive signals for attention and working memory in small studies, but the evidence is still too thin to rely on. Until larger studies are available, you can safely try it as a capsule or powder, but do not expect a dramatic effect.
Do ketone drinks do anything for your brain or performance?
For people with memory complaints the early signals are cautiously positive, but the studies are small and not conclusive. As a healthy athlete or average person, you have too little to go on to use ketone drinks with confidence.
What does alcohol do to your brain in the long term?
Long-term heavy drinking demonstrably damages the brain, in part irreversibly. Stopping helps, but after years of heavy use it should always be done under medical supervision.
What does excess weight do to your brain in the long run?
Excess weight harms your brain in multiple ways at once: less brain tissue, weaker connections and a higher risk of dementia. Exercise combined with diet appears to be able to partly reverse this, so losing weight is good for your brain too.
What does air pollution do to your brain in the long term?
Long-term exposure to air pollution, and fine particulate matter in particular, is associated with an increased risk of dementia and faster memory decline. The associations have been demonstrated in multiple human studies, but a direct cause-and-effect relationship has not yet been conclusively proven.