longevitywatch

Does using a night face cream actually help?

Yes · Preliminary evidence

A retinoid night cream has the best evidence base and can produce visible improvement after three months. For regular moisturising night creams the signals are positive, but the evidence is still thin, so it is wise to keep your expectations in check.

A retinoid night cream (a combination of alpha hydroxy acid and a retinoid) shows measurable improvements after 12 weeks: fewer fine lines, smaller pores, a more even skin tone, and better hydration. It also caused less redness than regular retinol or the prescription product tretinoin, which makes it practically interesting if you want to improve your skin without significant irritation. This is, however, a specific active ingredient, not a standard moisturising cream.

Routines that include a night cream show positive effects on multiple fronts. In women with sensitive skin, a routine containing a night cream improved overall skin appearance by 34%, compared with only 4% for a synthetic comparison routine. Other studies found improved hydration, smoother skin, and fewer crow's feet. The problem is that all of these studies tested day and night cream in combination, so it is not possible to isolate the effect of the night cream alone.

A small study with 15 participants tested a night cream containing donkey milk and found that it hydrated the skin more quickly than the accompanying day cream. The group was, however, too small to draw firm conclusions from.

In summary, night creams are rarely tested in isolation. What we do know is that routines that include a night cream consistently score better than routines without one. If you want a specific active ingredient that genuinely adds something at night, the retinoid combination cream has the strongest evidence base. For a standard moisturising night cream the evidence is thinner, but no negative effects have been found either.

The evidence
5 studies · 4 randomised trials · ≈ 303 participants

The evidence rests on four randomised studies and one study that is not further indexed, together involving a few hundred participants, predominantly women. The retinoid night cream has the most independent evidence behind it. For other night creams, they have consistently been tested in combination with day creams or other products, which means the separate effect of the night cream cannot be established. The researchers themselves identify this as a limitation in several of the studies.

Last checked: September 2026 · how this was judged
Related answers

Is an expensive face cream better than a cheap one?

A higher price does not make a face cream more effective or safer. It is better to pay attention to the ingredient list than to the price tag or marketing claims on the packaging.

No · Moderate evidence

Does resveratrol in skin cream actually do anything?

Resveratrol in skin cream demonstrably reaches the skin and has antioxidant activity, but whether it produces any visible effect as the sole active ingredient has not yet been proven. Combination products show promising results, but anyone buying a cream with resveratrol should be aware that the evidence for resveratrol itself remains thin.

Preliminary evidence

What actually works against skin aging?

Using sunscreen daily is the best-supported way to slow skin ageing, supplemented by not smoking, moderate alcohol consumption and sufficient sleep. Cosmetic options such as thread lifts and honey in creams have a weaker or not yet sufficiently proven basis and call for a critical weighing of the risks.

Moderate evidence

Does a face mask really work, or is it mostly just a treat for yourself?

An LED mask or a mask containing active ingredients such as salicylic acid works measurably better than doing nothing, but the effects are modest and many studies are small or commercially funded. Where possible, choose a mask with a proven active ingredient that matches your specific skin concern.

Yes · Moderate evidence

Does sleep deprivation age your skin faster?

Sleep deprivation demonstrably worsens your hydration, elasticity, and wrinkles, after as little as one poor night. Aim for consistently adequate sleep, and combine it with sun protection for the best result.

Does a vampire facial (PRP) work against skin ageing?

PRP injections produce a modest, likely genuine improvement in skin texture and elasticity, but do not work for everything (hydration and pigmentation spots respond poorly). If you want to try it, choose a clinic that provides clear information about the protocol used.

Yes · Moderate evidence
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