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Is L-theanine good for stress and sleep?

Yes · Moderate evidence

For everyday mental stress and mild sleep problems, multiple studies support 200 mg of L-theanine per day. For an anxiety disorder or serious sleep complaints, the evidence is too thin to rely on without guidance from your doctor.

What does workDoes ashwagandha really work against stress?

Yes, for everyday mental stress and mild sleep problems, L-theanine is worth trying. Choose a capsule or tablet containing pure L-theanine, with 'L-Theanine 200 mg' on the label. If you want to try it for stress or sleep, take 200 mg per day and give it at least four weeks. It is better to avoid combination products with multiple ingredients: with those, you cannot tell whether it is the L-theanine that is doing anything. According to the research, it makes no difference whether you are male or female.

A study of 30 healthy adults (200 mg per day, four weeks) found less stress, a shorter time to fall asleep and less sleep disruption compared with a placebo. A systematic review of nine studies confirms the effect on stress. However, two of the researchers worked for the manufacturer of the product, and another study saw no effect of 200 mg during an intense, physically activating stressor in virtual reality. L-theanine therefore appears to work better for mental, everyday stress than for severe or acute physical pressure.

Doses of 200 to 400 mg per day for up to eight weeks appear to be safe. A review article reports no liver toxicity for this amino acid at that dosage, in contrast to green tea extracts. Long-term data are still lacking.

Do you have a generalised anxiety disorder and are you already taking antidepressants? In research, people with that condition received 450 to 900 mg per day as a supplement to an antidepressant for eight weeks, but that did not work better than a placebo for anxiety symptoms. Discuss this with your doctor.

The evidence
8 studies · 5 randomised trials

Based on 2 systematic reviews, 5 randomised controlled studies and 1 narrative review. One RCT has a conflict of interest (manufacturer paid the authors). One RCT involving a combination supplement cannot be attributed to L-theanine alone.

Last checked: September 2026 · how this was judged
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