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BiomarkerCholesterol
Last scientific update: jun 2026
Cholesterol is a fatty substance in your blood that your body needs, but in excess it contributes to clogged arteries. What matters most is the harmful particles (LDL and ApoB).
Cholesterol at a glance
ImportanceRisk factor for heart and vesselsStrong
Best measureApoB, better than LDLStrong
LowerableYes, lifestyle and statinsStrong
ContextThe whole risk picture counts
With cholesterol, what matters most is the harmful particles (LDL and ApoB) and your whole risk picture, not a single number.
36 studies5 answersupdated jun 2026
Evidence per claim
ApoB is a more precise measure than ordinary LDL
View evidence →A slightly raised cholesterol is not always worrying
View evidence →Eggs are usually not bad for your cholesterol
View evidence →Raising HDL is hard and less decisive than thought
View evidence →Practical use
For whom
Anyone who wants their cardiovascular risk in view; have ApoB tested if needed.
Not for whom
Do not fixate on a slightly raised number without the rest of your risk.
Usual dose
Limit saturated fat, add fibre and exercise; statins with raised risk.
Key caveats
Total cholesterol says little; look at LDL/ApoB and the whole picture.
What we know, and don't
Known
The harmful particles (LDL/ApoB) matter most
Lowering reduces risk
Eggs are fine for most people
Not yet
The ideal target per person
How much HDL really matters
The best diet per individual
Common misconceptions
"All cholesterol is bad."
Incomplete. You need it; the issue is too many harmful particles.Strong evidence
"Eggs raise your cholesterol dangerously."
False. For most people that effect is small.Moderate evidence
How Cholesterol connects
Effects
Conditions
Related
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