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Cholesterol

Cholesterol is a fatty substance in your blood that your body needs, but in excess it contributes to clogged arteries. What matters most is the harmful particles (LDL and ApoB).

Cholesterol at a glance

ImportanceRisk factor for heart and vesselsStrong
Best measureApoB, better than LDLStrong
Can it be lowered?Yes, lifestyle and statinsStrong
ContextThe whole risk picture counts
86 studies13 answersupdated Nov 2026
Evidence per claim
ApoB is a more precise measure than ordinary LDL
View evidence →
Strong
A slightly raised cholesterol is not always worrying
View evidence →
Moderate
Eggs are usually not bad for your cholesterol
View evidence →
Moderate
Raising HDL is hard and less decisive than thought
View evidence →
Moderate
Practical use

For whom

Anyone who wants their cardiovascular risk in view; have ApoB tested if needed.

Not for whom

Do not fixate on a slightly raised number without the rest of your risk.

In practice

Limit saturated fat, add fibre and exercise; statins with raised risk.

Key caveats

Total cholesterol says little; look at LDL/ApoB and the whole picture.

What we know, and don't

Known

The harmful particles (LDL/ApoB) matter most
Lowering reduces risk
Eggs are fine for most people

Not yet

The ideal target per person
How much HDL really matters
The best diet per individual
Common misconceptions
"All cholesterol is bad."
Incomplete. You need it; the issue is too many harmful particles.Strong evidence
"Eggs raise your cholesterol dangerously."
False. For most people that effect is small.Moderate evidence
Latest news on cholesterol
Statin use associated with slower bone density decline in postmenopausal women29 OctGut bacterium slows artery plaque in mice almost as well as a statin11 OctStatins may cut dementia risk in type 2 diabetes11 SepStatins keep hearts of people with obesity healthy3 JulCholesterol in ear cells determines if you keep hearing4 Jun
Heard on podcasts

What popular health podcasts claimed about cholesterol, checked against the research.

The Drive · Michael DavidsonPartly
“Maintaining an LDL cholesterol level below 80 mg/dL throughout life prevents the development of cardiovascular disease.”
What the research says →
Dave AspreyPartly
“Eating butter raises the level of protective HDL cholesterol in the blood.”
What the research says →
Thomas DeLauerPartly
“Raw honey lowers fasting blood glucose, total cholesterol and triglycerides, and raises HDL cholesterol.”
What the research says →
Cholesterol: what's new, and what holds up

We follow the latest research on cholesterol and listen to leading health podcasts, and we check what they claim. You'll get one email on Thursdays with what matters, and only when there's something new.

You can add more topics later, such as exercise or sleep.

Related topics
Effects
Conditions
Cardiovascular disease
Related
LDL / ApoB
Triglycerides