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Chronic low-grade inflammation

Chronic low-grade inflammation is a smouldering, long-term activation of your immune system that you barely notice but that is measurable in blood markers such as hsCRP. It is driven by factors including excess body weight, sleep deprivation, a disrupted gut microbiome, gum disease and physical inactivity. Unlike acute inflammation after an injury, this form does not resolve on its own and sustains itself through multiple biological feedback loops.

Related questions
Does turmeric help against inflammation?
Yes · Moderate evidence · 18 studies
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Yes · Moderate evidence · 8 studies
Does quercetin work against ageing and inflammation?
Preliminary evidence · 8 studies
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Preliminary evidence · 8 studies
Can long-term inflammation in your body cause cancer?
8 studies
Does regular exercise help against that creeping chronic inflammation?
Yes · Moderate evidence · 8 studies
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8 studies
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8 studies
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Yes · Moderate evidence · 8 studies
Can your gut microbiome influence inflammation in your body?
8 studies
What does excess weight do to your inflammation levels?
7 studies
What is the link between high blood pressure and inflammation?
7 studies
Does chronic inflammation accelerate the ageing of your cells?
7 studies
What does my CRP value (inflammation) say about my heart?
5 studies
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Latest news on chronic low-grade inflammation
Inflammatory signal in aging cells selectively silenced in lab breast cancer cells30 OctPlant compound eases joint inflammation in rats via fat metabolism26 OctType 2 immunity acts as a brake on chronic inflammation in aging24 OctGut microbiome predicts inflammation better than age20 OctAncient viral DNA in our cells fuels inflammation with age18 Oct
Heard on podcasts

What popular health podcasts claimed about chronic low-grade inflammation, checked against the research.

ZOE · Luke O'NeillPartly
“Chronic low-grade inflammation accelerates the biological ageing process and shortens lifespan.”
What the research says →
ZOE · Elaine DennisonPartly
“Chronic low-grade inflammation and prolonged elevated cortisol levels stimulate bone resorption relative to bone formation.”
What the research says →
Lifespan · Matthew LaPlantePartly
“Chronic low-grade inflammation accelerates cellular ageing and contributes to conditions such as diabetes, heart disease and Alzheimer's disease.”
What the research says →
Chronic low-grade inflammation: what's new, and what holds up

We follow the latest research on chronic low-grade inflammation and listen to leading health podcasts, and we check what they claim. You'll get one email on Thursdays with what matters, and only when there's something new.

You can add more topics later, such as exercise or sleep.