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Does your libido decline after 40, and what can you do?

Yes · Moderate evidence

A decline in libido after 40 is normal but not inevitable. For men with a confirmed low testosterone level and associated symptoms a well-supported treatment exists, and for women around the menopause hormone therapy offers concrete help, particularly for vaginal complaints.

A decline in libido after 40 is very common for both men and women, but it is by no means an inevitable fate. In women, the ovaries gradually produce less oestrogen and testosterone around the menopause. Up to half of sexually active older women are affected by this, with reduced desire topping the list. Falling oestrogen levels can also cause vaginal dryness, which makes sex painful. Even so, the majority of older women continue to consider sex important.

In men, testosterone declines gradually with age. Approximately 30% of men between the ages of 40 and 79 have a measurable deficiency, with possible consequences including reduced interest in sex, erectile problems, muscle loss and increased abdominal fat. Being overweight, having diabetes and having high blood pressure all raise that risk. This therefore affects a substantial minority, not everyone.

For men who have both symptoms and a demonstrably low testosterone level, testosterone therapy is a serious option. The large TRAVERSE trial (more than 1,100 participants) showed that the therapy clearly improved sexual activity and desire, an effect that lasted two years1. Erectile problems were not resolved by the therapy in that same study. Men with normal testosterone levels gain nothing from it; it does not work as a general anti-ageing remedy.

For women around the menopause, hormone therapy and lifestyle adjustments are the best-known options. Hormone therapy demonstrably helps with sexual complaints caused by the loss of hormones, and the evidence is strongest for vaginal dryness and pain during sex. Non-hormonal approaches also exist, but concrete effect sizes have not been well established in the available research.

DHEA is a substance the body converts into oestrogen and testosterone, and its levels fall sharply with age. In women over 70 there are indications of a limited positive effect on libido, but the results are contradictory. The long-term risks for cardiovascular disease and hormone-dependent cancers have not been sufficiently studied, and researchers therefore explicitly advise against DHEA supplementation in older adults. Are you using dutasteride or finasteride for hair loss? These medications can also reduce libido as a side effect. Discuss this with your doctor.

The evidence
8 studies · 1 randomised trial · ≈ 1,161 participants

The claims are based on epidemiological studies, a large randomised trial (TRAVERSE, PMID 37589949) and review articles on the menopause and low testosterone in men. The evidence for testosterone therapy in men is the strongest. For hormone therapy in women the evidence is moderate but consistent. For DHEA the evidence is thin and contradictory.

Last checked: September 2026 · how this was judged
Related answers

How can you improve sperm quality and quantity when you are over 40?

No interventions have yet been proven to reliably improve sperm quality in men over 40; antioxidants show a signal but the effect disappears in the higher-quality studies. Discuss your situation with a doctor, especially if you are actively trying to conceive.

Preliminary evidence

What can help women increase their libido?

There are several well-supported options depending on your life stage: for women after menopause, transdermal testosterone has the strongest evidence base, and mindfulness therapy works for a broader group. Always discuss medication options with your doctor, as availability and long-term safety require a personal assessment.

Moderate evidence

Does testosterone decline in men with age?

Testosterone genuinely declines in men with age. Testosterone therapy is well supported only in men with established hypogonadism (a medically confirmed testosterone deficiency) who also have symptoms, particularly for sexual function. If you have symptoms, always have the underlying cause investigated first.

Yes · Strong evidence

Does my growth hormone decline with age, and does that matter?

Your growth hormone does indeed decline sharply with age. Reversing that with hormone injections offers little benefit in healthy older adults and carries health risks, including an increased risk of cancer.

Yes · Strong evidence

Does testosterone help after 50, and is it dangerous?

Testosterone can be worthwhile for men over 50 with a medically confirmed testosterone deficiency, but it is not a treatment for everyone who is getting older: the benefits are real, the risks are too, and a doctor must establish the indication.

Yes · Strong evidence

Can exercise really improve your hormone levels as you get older?

Yes, exercise demonstrably raises several hormone levels in people over 40. The strongest practical benefit lies in muscle preservation: strength training is the most effective approach for that, regardless of which type of training you choose.

Yes · Moderate evidence
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