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Which symptoms are most common during menopause?

Most women experience multiple complaints simultaneously during the menopause transition. Joint and muscle pain, fatigue, sleep problems and hot flushes are the most common, but memory complaints and a low mood are also very prevalent.

Joint and muscle pain is the most widely reported physical complaint during the menopause transition worldwide. In a meta-analysis of nearly 482,000 women, an average of 65% were affected1. European and American surveys confirm this with figures of 68 to 69%. Back pain is also part of this picture: in Taiwanese research 58% reported back pain, and in Spanish research lower back pain was even identified as the most bothersome complaint.

Hot flushes and night sweats are the most characteristic complaints. Yet the percentages vary considerably: in high-income countries around 50% are affected, compared with 66% in low-income countries2. The further the transition progresses, the more they increase: severe hot flushes were reported by 9% before menopause and by 37% in the late perimenopause3. They affect both daily activities and work performance.

Fatigue and sleep problems largely go hand in hand. In large international surveys, 66 to 75% of women felt tired or exhausted. Difficulty falling or staying asleep was reported by 60 to 69%1,4. Hormonal changes and hot flushes both contribute to those poor nights. After menopause, the risk of sleep apnoea also increases, probably due to hormonal changes and fat accumulation5.

Vaginal dryness almost doubles after menopause: from 21% in premenopausal women to 45% in postmenopausal women6. This is directly linked to the decline in oestrogen. Weight gain is not the most common complaint, but it is rated as the most bothersome in European and American surveys.

On the mental health side, memory loss ranks high on the list: 67% of women in Taiwanese research named this as a top complaint7. A low mood was reported by 59%; in South America, rates of depression are notably high compared with other regions. Persistent hot flushes and sleep problems are also possible predictors of later cardiovascular problems, which is an additional reason to consult your general practitioner or gynaecologist if symptoms are severe8.

The evidence
8 studies · 1 meta-analyses · ≈ 482,000 participants

Based on several large international surveys and a meta-analysis of approximately 482,000 women (PMID 38956480, 34033602, 36306669, 33048863, 40720963). Additional studies address sleep apnoea (PMID 31097176), early menopause transition research (PMID 15062730) and cardiovascular risks (PMID 29393299). Most associations are observational. For hot flushes and vaginal dryness, a causal link with hormonal changes is considered likely.

Last updated: June 2026
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