In a mouse model of spinal disc degeneration, a cheap, decades-old drug combination beat a newer and more expensive competitor.
As people age, their risk of joint inflammation rises — not just because joints wear down, but because the body quietly loses one of its own braking systems.
Cartilage heals slowly even in young people, but in older age that capacity nearly disappears.
Gout has long been typecast as an affliction of older, wealthy men. But it’s now appearing earlier in life, in more diverse populations, and its biological mechanisms are proving more complicated than…
Worn-down spinal discs are behind much of the back pain that becomes nearly universal with age.
Back pain from worn-down spinal discs is one of the most common complaints in aging adults.
Cartilage is one of the body’s least regenerative tissues. Now researchers have found it carries a built-in molecular brake against its own destruction — one that appears to fail precisely when it…
Spinal disc degeneration is one of the most common causes of chronic lower back pain in older people — and so far, there is little to offer beyond painkillers and surgery.
Spinal disc degeneration affects almost everyone as they age and is a leading cause of chronic back pain.