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Answers to the questions you ask yourself about healthy aging.

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InterventionsRapamycin, metformin, GLP-1 and other widely-discussed compounds.
  • What are the best proven methods to prevent and treat migraines?
  • What health benefits do GLP-1 medications offer beyond weight loss?
  • Does alpha-ketoglutarate work against ageing?
286 answers · 1,880 studies
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MetabolismBlood sugar, insulin and weight, the engine of aging.
  • What is spermidine and where is it found?
  • What does taurine do in your body?
  • Does berberine help with weight loss?
120 answers · 805 studies
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Heart & vesselsCholesterol, blood pressure and vascular age, the biggest cause of death.
  • What health benefits do GLP-1 medications offer beyond weight loss?
  • How much magnesium do you need per day?
  • How does the lipid profile change after menopause, and what can you do about it?
110 answers · 722 studies
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HormonesTestosterone, menopause and hormone therapy as you age.
  • How do you get your hormone levels tested during perimenopause?
  • Which hormone levels are tested during menopause and what do the results mean?
  • How does the lipid profile change after menopause, and what can you do about it?
85 answers · 584 studies
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Immune systemInflammation, defence and how your immune system ages.
  • Does quercetin help with hay fever and allergies?
  • Does covid-19 have a lasting effect on the immune system?
  • Does long-term antibiotic use weaken your immune system?
81 answers · 553 studies
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SleepHow much sleep you need and what poor sleep does.
  • Are sleep trackers accurate enough to help you improve your sleep?
  • How much melatonin should you take to sleep better?
  • Does the sleepy girl mocktail (magnesium with cherry juice) help you sleep?
80 answers · 525 studies
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SkinSkin aging and what actually helps against it.
  • What do we know about berberine patches?
  • What are the proven health benefits of snail mucus for the skin?
  • Does omega-3 protect your skin from sunburn?
74 answers · 477 studies
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Gut & microbiomeGut flora, fibre and fermented foods.
  • Which fermented products have the greatest effect on gut health?
  • Is fermented food good for your health and your microbiome?
  • Does long-term antibiotic use weaken your immune system?
72 answers · 489 studies
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CancerScreening, lifestyle and what shapes your cancer risk.
  • Does linoleic acid in tissue increase the risk of skin cancer?
  • What is the role of chronic inflammation in the development of cancer?
  • Which cancer screenings are worthwhile, and from what age?
68 answers · 471 studies
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Aging clocksBiological age, epigenetic clocks and biomarkers of aging.
  • Does alpha-ketoglutarate work against ageing?
  • What can you expect from a longevity clinic in the Netherlands?
  • Does your telomere length tell you anything useful about your health?
66 answers · 430 studies
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Cells & DNATelomeres, mitochondria, senescence and NAD , aging at the cellular level.
  • What do mitochondrial mutations mean for how quickly you age?
  • Can you repair DNA damage, or can you only prevent it?
  • What exactly does senescence do to your cells as you age?
65 answers · 460 studies
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BonesBone density, osteoporosis and strong bones in later life.
  • Which supplements are proven to help strengthen bones?
  • Why do bones become more brittle after menopause, and what can help?
  • What does a DEXA scan tell you that a regular bone density measurement does not?
65 answers · 448 studies
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