Heart & vessels
Cholesterol, blood pressure and vascular age, the biggest cause of death.
126 answers, from 847 studies
Last updated: October 2026
Key questions
What does your vascular age tell you about your health?
A high vascular age on the measurement is a serious signal: your risk of cardiovascular disease, dementia, and premature death…
How can poor oral health and periodontitis raise your blood pressure?
Gum disease is clearly associated with higher blood pressure, and there is good evidence that it genuinely contributes to it.…
Are erectile problems an early sign of heart disease?
Erectile problems caused by poor blood flow precede a heart attack or stroke by an average of 2 to 5 years. If you have this…
What does testosterone therapy tell us about all-cause mortality?
Testosterone therapy does not demonstrably reduce the chances of dying from any cause, but does not increase them either. Do…
What does eating an avocado every day do for your health?
Eating an avocado every day probably has beneficial effects on your cholesterol, especially when you use it to replace other,…
Does intermittent fasting lower your cholesterol?
Intermittent fasting probably lowers total cholesterol and LDL modestly, but its effect on 'good' HDL cholesterol is unclear…
Yes · Moderate evidence
What are the benefits of combining sauna with an ice bath?
The combination of sauna and ice bath demonstrably lowers cortisol and promotes blood flow after exercise, but whether it…
How many steps per day lower your risk of dying?
More steps per day is strongly associated with a lower risk of dying, and the benefit starts at as few as 3,000 to 4,000…
Strong evidence
What is the sitting-rising test, and what does it say about your life expectancy?
A low SRT score is associated with a considerably higher risk of death, but that does not mean the score determines your fate.…
What your resting heart rate says about your life expectancy
A higher resting heart rate is clearly and consistently linked to a higher risk of premature death, even after taking other…
How much exercise per week lowers your risk of dying?
Even a quarter of an hour of exercise a day makes a measurable difference; the biggest gain comes from going from nothing to…
Strong evidence
Do you live longer if you eat more salt?
Eating more salt does not lead to a longer life. At the individual level, it demonstrably increases the risk of cardiovascular…
No · Strong evidence
Can GLP-1 agonists improve heart function?
Semaglutide and tirzepatide demonstrably reduce the chance of heart failure worsening in people with a specific form of heart…
Yes · Strong evidence
Is eating 800 grams of fruit and vegetables a day healthier than the standard guideline?
More than 400 grams a day helps, but whether 800 grams is clearly healthier than 400 grams depends on your goal: for heart and…
Moderate evidence
How reliable are the heart rate scores from your wearable?
A good wearable measures resting heart rate reliably, but HRV scores and readiness are less accurate than they appear. Use…
How early should you start lowering your LDL cholesterol?
Starting as early as possible pays off: LDL damage accumulates from childhood, and every year that your LDL remains lower…
Strong evidence
Are calcium supplements bad for your heart?
Calcium supplements may be associated with an increased heart risk, but not all studies confirm this. It is best to get…
Moderate evidence
Does eating spicy food help you live longer?
Eating spicy food regularly is linked to a lower chance of dying early, but whether it is the cause is not yet known. With…
Moderate evidence
Does reducing inflammation help your heart in the long term?
Targeted treatment to reduce inflammation, particularly with low-dose colchicine, measurably reduces the risk of serious heart…
Yes · Moderate evidence
What health benefits do GLP-1 medications offer beyond weight loss?
In type 2 diabetes, GLP-1 medications offer well-supported protection for the heart, blood vessels, and kidneys; there are…
Strong evidence
Is the taurine in energy drinks harmful?
Taurine in energy drinks does not appear to be harmful in the short term, but the real risks lie in the caffeine and sugar. If…
No · Preliminary evidence
How much magnesium do you need per day?
Research suggests that your body reaches balance at around 165 mg per day, but official recommendations are higher and there…
Moderate evidence
How does your lipid profile change after menopause?
After menopause, the lipid profile demonstrably worsens due to the decline in oestrogen. Regular exercise and moderately…
Moderate evidence
Do white spots on the brain increase the risk of dementia?
Pronounced white spots on a brain scan demonstrably increase the risk of dementia, but not every spot is equally concerning.…
Strong evidence
Can you remove microplastics from your blood vessels?
No method exists to selectively remove microplastics from your blood vessels, and research into this has not been conducted…
No · Preliminary evidence
How much does ultra-processed food increase your risk of dying?
A high intake of ultra-processed food is associated with a higher risk of dying, but estimates vary widely (2% to 21%) and…
Is your oral health linked to cardiovascular disease?
Serious gum disease is demonstrably associated with a higher risk of cardiovascular conditions and high blood pressure; that…
How many sauna sessions per week produce health benefits?
Even 2 to 3 sessions per week is associated with measurable health benefits; those who go 4 or more times appear to benefit…
Moderate evidence
Does taking omega-3 help you stay healthy for longer?
Omega-3 reliably lowers blood fats, but the evidence that it helps you live longer or stay healthier is limited. If you…
Moderate evidence
Does sitting all day increase your risk of heart problems?
Sitting a lot increases your risk of heart failure and heart-related mortality, even if you exercise regularly. Just 30…
Yes · Strong evidence
Can clogged blood vessels be cleaned up again?
Early arterial hardening can partly be reversed, especially with strong LDL reduction using statins or newer medicines. The…
Yes · Moderate evidence
Does black seed oil work as a supplement?
Black seed oil has shown measurable effects on blood fats, blood pressure and inflammatory markers in multiple meta-analyses,…
Yes · Moderate evidence
Does nattokinase work against blood clots and for your heart?
The best available research shows that nattokinase has no demonstrable effect on arterial hardening or blood pressure after…
No · Preliminary evidence
Does hormone therapy help women age more healthily?
Hormone therapy relieves menopausal symptoms well and shows positive indications for bones and metabolism, but the effects on…
Moderate evidence
What does menopause do to your risk of cardiovascular disease?
Menopause demonstrably increases your risk of cardiovascular disease, primarily through unfavourable changes in fat…
What does a daytime nap do for your health?
A daytime nap improves alertness, memory and concentration, especially if you take it before 13:00 and keep it between 20 and…
Do you really need to take 10,000 steps a day?
No, 10,000 steps is not a scientific standard but a marketing slogan. Depending on your age, you can gain substantial health…
No · Strong evidence
Which supplements are best avoided in combination with blood thinners?
Several supplements can strengthen or weaken the effect of blood thinners; always mention them to your pharmacist or doctor…
Preliminary evidence
How much omega-3 with EPA and DHA do you need per day?
There is no fixed omega-3 dose for everyone: for heart protection, around 1 g of EPA+DHA per day is the most studied amount;…
Moderate evidence
Does poor sleep really shorten your life?
Consistently sleeping too little is associated with a measurably higher risk of earlier death and serious illness; the…
Are ultra-processed products bad for your longevity?
Eating a lot of ultra-processed products is associated with a shorter lifespan and more chronic disease, but the effect varies…
Yes · Moderate evidence
Does the form of omega-3 you choose matter?
The form matters, but the meal you take omega-3 with matters at least as much: always take ethyl esters with a fatty meal,…
Preliminary evidence
Should you take vitamin D together with vitamin K2?
For osteoporosis, there is reasonable evidence that vitamin K2 and D3 together do more for bone density than either one alone;…
Moderate evidence
Does your resting heart rate say anything about how fast you are ageing?
A structurally high resting heart rate, certainly above 80 to 90 beats per minute, is associated with a clearly higher risk of…
What is the link between fatty liver and type 2 diabetes?
Fatty liver and type 2 diabetes reinforce each other: they share the same underlying mechanism and roughly double each other's…
Can you drink coffee during intermittent fasting?
Black coffee fits comfortably within intermittent fasting and is explicitly listed as a fasting drink in dietary guidelines.…
Yes · Moderate evidence
Does smoking also age your skin from the inside?
Smoking does not only age the outside of your skin; it damages blood vessels, protective barriers and inflammation levels from…
What is the link between high blood pressure and inflammation?
High blood pressure and inflammation reinforce each other, and higher levels of inflammation signals in the blood mean a…
Can chronically poor sleep cause me to have a stroke at a younger age?
Chronically poor or insufficient sleep is associated with an increased risk of cardiovascular disease, including stroke. If…
Yes · Strong evidence
Can intense exercise actually make you age faster?
Structurally overtraining can accelerate ageing processes, while regular moderate to intense exercise actually protects you.…
Preliminary evidence
Can your gut microbiome influence your risk of heart disease?
Your gut microbiome influences your heart health through metabolic by-products that can promote arterial hardening, high blood…
Yes · Moderate evidence
Can your gut microbiome affect your cholesterol?
Your gut microbiome influences your cholesterol through bile acid conversion and the fermentation of fibres. Eating more fibre…
Which blood markers can tell you how fast you are biologically ageing?
Blood markers such as protein profiles, DNA-tag patterns, telomere length and standard inflammation markers each offer their…
What does high cholesterol do to your brain as you age?
High cholesterol in middle age likely increases the risk of dementia, but at older ages the relationship is less clear and…
Can sleep deprivation raise your blood pressure?
Yes, sleep deprivation demonstrably raises blood pressure in adults. Seven to eight hours of sleep per night is the most…
Yes · Strong evidence
What is the link between gum disease and heart disease?
There is a consistent association between gum disease and a higher risk of heart disease, although it has not been proven that…
How bad is sitting for too long for your blood sugar and metabolism?
Sitting for long uninterrupted periods noticeably impairs your blood sugar and metabolism, but short breaks of 2-3 minutes of…
What does alcohol do to your gut microbiome?
Chronic heavy drinking demonstrably disrupts the gut microbiome, with consequences for the heart and liver. Moderate drinking…
Does your immune system age at a different rate than your heart?
Yes, your immune system and heart age at measurably different rates, and an ageing immune system is more strongly linked to a…
What does a low-carbohydrate diet do to your LDL cholesterol?
A low-carbohydrate diet raises LDL cholesterol modestly in most people, and sometimes substantially. If you already have…
Can statins (cholesterol-lowering medications) affect your bones?
Statins show positive effects on bone in laboratory and animal research, but randomised trials in humans do not confirm this.…
Moderate evidence
What does long-term sleep deprivation do to your heart?
Chronically sleeping too little demonstrably increases your risk of a heart attack and high blood pressure, and genetic…
Can high blood pressure in your 40s cause dementia later in life?
High blood pressure in your forties demonstrably increases your risk of dementia later in life, and early treatment appears to…
What is visceral fat and why is it more dangerous than subcutaneous fat?
Visceral fat is more dangerous than subcutaneous fat because it sends irritating substances and fatty acids directly to the…
What are the earliest signs of insulin resistance?
Early signs of insulin resistance are measurable long before a diabetes diagnosis: elevated fasting insulin, abdominal fat,…
Can your HbA1c also be too low?
An HbA1c below 5.0% is associated with an increased risk of death in people without diabetes, although this is likely a signal…
Yes · Moderate evidence
What does your HbA1c tell you about your risk of diabetes and ageing?
An elevated HbA1c, even well below the official diabetes threshold, is associated with a greater risk of diabetes, kidney…
Who should have their ApoB measured?
Measuring ApoB is worthwhile for more people than current guidelines suggest: not only in cases of elevated blood fats, but…
Moderate evidence
How does too much LDL or ApoB lead to clogged arteries?
Too many LDL and apoB particles sets off a well-established chain reaction that gradually clogs arteries. Having your apoB…
How do you lower an ApoB level that is too high?
An ApoB level that is too high is very treatable, and several proven agents are available. Statins are the first choice; PCSK9…
Strong evidence
What is a healthy ApoB level?
There is no fixed 'healthy' ApoB value, but below 82 mg/dL the risk of a stroke already decreases measurably. ApoB offers…
What does your ApoB value tell you about your risk of cardiovascular disease?
ApoB gives a more accurate picture of your cardiovascular disease risk than standard LDL cholesterol. Ask your doctor to also…
Is an ECG from your smartwatch actually useful?
For detecting atrial fibrillation, a smartwatch ECG can be useful, especially as a complement to medical monitoring. For other…
Yes · Moderate evidence
Does gratitude or optimism help your health and longevity?
Greater optimism is linked, across several large, long-running studies, to a considerably lower risk of dying from heart and…
Yes · Moderate evidence
Which foods or supplements keep your blood vessels healthy?
The Mediterranean diet most demonstrably lowers your risk of heart and blood vessel disease. Individual supplements do not help.
Moderate evidence
How much does a consistent sleep schedule really matter?
A consistent sleep schedule really does matter. Irregular sleep times are strongly associated with more depression, anxiety, a…
Is high blood pressure at night more dangerous than during the day?
High blood pressure at night is more dangerous than high blood pressure during the day. Have a 24-hour measurement taken if…
Do omega-3s help against heart rhythm disorders?
Omega-3 supplements do not help against heart rhythm disorders and at higher doses actually increase the risk of atrial…
No · Strong evidence
Is farmed fish just as healthy as wild fish?
Three to four portions of fish per week is healthy for most people. Whether farmed fish and wild fish are nutritionally…
Strong evidence
Is wholegrain bread really that much better than white bread?
Large-scale observational research consistently points in the same direction: wholegrain is better for your heart, your weight…
Yes · Moderate evidence
How many fruits and vegetables do I actually need per day?
Five portions of fruit and vegetables per day (two pieces of fruit, three serving-spoon scoops of vegetables) is the number…
What does the menopause do to my heart and bones in the long term?
In the long run, menopause increases your risk of cardiovascular disease and bone loss, and that effect is greater with an…
Can losing weight noticeably improve my blood pressure and cholesterol?
Losing weight noticeably lowers your blood pressure and improves your cholesterol profile, but which value improves the most…
Yes · Strong evidence
Should you worry about mildly elevated cholesterol?
A mildly elevated cholesterol is not automatically harmless: the overall picture, including triglycerides and lipoprotein(a),…
Moderate evidence
How harmful is prolonged stress really for my heart?
Prolonged stress measurably increases your risk of heart and vascular disease, particularly through work-related stress…
Is atrial fibrillation dangerous, and what can I do about it?
Atrial fibrillation substantially raises your chances of dying, heart failure, and stroke, and calls for active treatment.…
Yes · Strong evidence
When should you see a doctor about heart palpitations?
Palpitations are usually harmless, but can also be the beginning of a serious cardiac arrhythmia. If you also experience…
Moderate evidence
How often should I measure my blood pressure at home, and what is normal?
Measuring at home gives a more reliable picture than a single reading at the doctor's office: measure at least seven days,…
Moderate evidence
Do people age through different organs?
Yes, people age through different organ pathways. The science needed to map this precisely for each individual is promising,…
What is a healthy HDL (good cholesterol) level, and can I raise it?
Raising HDL through lifestyle is possible, but your genes set the ceiling. Lowering triglycerides through less sugar and…
Moderate evidence
What does my CRP value (inflammation) say about my heart?
A high hsCRP value points to chronic inflammation and predicts a clearly elevated long-term risk of cardiovascular problems,…
What is a healthy waist size, and why does it matter?
A larger waist is linked to a higher risk of early death, diabetes and heart disease, independently of overall body weight. If…
Do B vitamins (folate, B6) benefit your heart and brain?
Folate reduces stroke risk by around 16%, but most likely only when there is a deficiency. For broader cardiovascular risk and…
Moderate evidence
Does CoQ10 help your heart or your energy levels?
For people with moderate to severe heart failure, CoQ10 has the most convincing evidence; for energy or sports performance in…
Yes · Moderate evidence
Is loud snoring dangerous for my health?
Loud snoring is linked to serious health risks: hardening of the arteries, a higher chance of dying after a heart attack, and…
Yes · Moderate evidence
Does climbing stairs actually do anything for my heart?
Yes, climbing stairs genuinely does something for your heart. Climbing roughly 50 to 100 steps a day is associated with fewer…
Yes · Moderate evidence
How harmful are trans fats, exactly?
Industrial trans fats are demonstrably harmful to your heart and blood vessels, even in small amounts. Avoid them by checking…
Do omega-3 (fish oil) supplements benefit my heart?
Fish oil reliably lowers triglycerides and can slightly reduce the risk of a heart attack in people with existing heart…
Moderate evidence
How healthy are my blood vessels / what is my vascular age?
For a first impression of your vascular health, an ApoB blood test is the simplest and most accessible step; a CAC scan adds…
Does lowering my blood pressure really reduce my risk?
Lowering blood pressure genuinely works: your risk of stroke and other cardiovascular problems demonstrably decreases.…
Yes · Strong evidence
What is a healthy cholesterol level and when should I be concerned?
A normal LDL value does not give a complete picture of your cardiovascular risk. Ask your doctor about your remnant…
Moderate evidence
What is Lp(a) and is there anything I can do about it?
Lp(a) is a hereditary risk factor for cardiovascular disease that is independent of your LDL. Effective treatments are still…
Strong evidence
What does my blood pressure say about my long-term health?
A structurally high or strongly fluctuating blood pressure substantially increases your risk of stroke, heart attack and…
Does garlic help against high blood pressure or high cholesterol?
Garlic supplements measurably lower blood pressure in people with hypertension and have a modest favourable effect on…
Yes · Moderate evidence
Is high homocysteine bad for my heart?
High homocysteine is associated with a greater risk of cardiovascular disease, but whether it is the cause is not certain.…
Moderate evidence
How important is my triglyceride level?
Your triglycerides are a meaningful risk indicator, especially in combination with abdominal fat or a high blood sugar level.…
Does my heart rate variability (HRV) tell me anything about my health?
A higher HRV is associated with better health and greater resilience. Slow breathing is the most accessible and best-supported…
What is a healthy resting heart rate?
A resting heart rate between 60 and 80 beats per minute is considered generally normal, but lower is fine for active people,…
Does vitamin K2 help your bones and blood vessels?
For bones in women after the menopause the evidence is reasonably strong; combining K2 with vitamin D gives the greatest…
Yes · Moderate evidence
Does dark chocolate or cocoa benefit your heart?
Dark chocolate with a high cocoa content appears to be good for your heart, but the evidence is still based on studies that…
Yes · Moderate evidence
Are nuts good for your heart and your weight?
For most people, a daily handful of nuts is a well-supported choice for a healthier heart. Anyone wanting to lose weight or…
Yes · Moderate evidence
How healthy is olive oil and what is it good for?
Olive oil, and extra-virgin olive oil in particular, is well supported as protective for the heart and blood vessels,…
Are eggs bad for your cholesterol?
Eggs are not automatically bad for your cholesterol; the rest of your diet, especially the amount of saturated fat, carries…
Moderate evidence
Is green tea really as healthy as they say?
Two to three cups of green tea a day fits well into a healthy lifestyle and is probably safe, but do not take concentrated…
Moderate evidence
How bad is eating a lot of salt for me?
Eating a lot of salt is clearly harmful to your blood pressure and your heart, and the risk grows with the amount consumed.…
Is the Mediterranean diet really good for your heart, and why?
For people at increased heart risk, the Mediterranean diet is the best-supported dietary choice currently available. Both…
Yes · Strong evidence
Is coffee good or bad for your heart?
For most healthy adults, three to four filtered cups per day is associated with a beneficial effect on the heart and blood…
Moderate evidence
Is interval training (HIIT) better for my heart than regular cardio?
For cardiac patients in rehabilitation, HIIT produces greater fitness gains on average than regular cardio, but this does not…
Moderate evidence
Is taking a daily aspirin smart or dangerous?
Whether a daily aspirin is smart or dangerous depends entirely on your age and medical profile. Take aspirin only on a…
Moderate evidence
Should I take statins if I have (not yet) had a heart problem?
Whether statins are worthwhile depends on your personal risk. At a calculated 10-year risk of 10% or higher and at least one…
Strong evidence
Is a calcium score of my heart worth doing?
For people between 40 and 75 years old in a grey zone regarding statins, a calcium score is a well-supported tool for making a…
Yes · Strong evidence
How dangerous is belly fat?
Belly fat is a serious risk factor for cardiovascular disease, heart failure, and early death, and the risk grows the longer…
Is ApoB more important than regular cholesterol (LDL)?
ApoB consistently predicts cardiovascular disease better than LDL cholesterol. If you want to know how high your risk truly…
Yes · Strong evidence
Does unhealthy gums affect my heart?
People with serious gum disease show clearly higher risks of heart attack, stroke and premature death in large-scale research.…
Yes · Moderate evidence
Does coffee lower the risk of premature death?
Coffee (3 to 4 cups per day, preferably in the morning and without much sugar) is associated with less early death in large…
Yes · Strong evidence
Does regular sauna use help you live longer?
Regular sauna use is consistently linked to a lower risk of early death and heart problems in studies following large numbers…
Yes · Moderate evidence
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Artery plaque found in adults as young as eighteen
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Transplanted hearts age with their recipient
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Low heart risk at midlife predicts healthy aging
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Chronic inflammation fuels arterial plaque buildup
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Scar tissue in the aging heart traced to one receptor
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Eye scans predict heart problems years earlier
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Vascular muscle turns into plaque fuel
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Heart cells tug against each other to stay healthy
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The spleen controls platelet activity across the body
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Fat cells fuel artery plaque via inflammation
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A blood protein links APOE4 gene to Alzheimer’s vessel damage
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Statins may cut dementia risk in type 2 diabetes
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Immune signatures may flag heart disease early
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Diabetes drug protects the heart via unexpected pathway
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Short intense exercise triggers the widest signal wave
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Healthy midlife blood vessels add twelve dementia-free years
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Brain blood vessels respond differently per cortical layer
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Heart vessels rebuild themselves after a heart attack
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Aged fat cells fuel inflammation via blood protein
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High blood pressure harms multiple organs at cell level
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Cell pH sensor mapped at atomic level for first time
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Gut-derived TMAO raises atrial fibrillation risk
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1 min
Blocking inflammation does not always protect the heart
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Heart cell DNA is exquisitely sensitive to one protein
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Getting your heart checked, from cheap to expensive
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4 min
Single-cell mapping reveals early changes in heart failure
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Gene activity mapped across cohorts reveals aging risk
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Doctors may get paid more to help patients quit smoking
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Mediterranean diet boosts protective proteins from mitochondria
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Aortic dissection: aging’s silent vascular threat
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Serotonin speeds heart valve damage in some people
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Blood vessel cells fuel inflammation by clearing mitochondria
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1 min
Statins keep hearts of people with obesity healthy
People with obesity have worse cardiovascular health. That is the conventional wisdom. A 25-year study now challenges that…
2 min
Network medicine maps old drugs to aging pathways
Could a blood pressure pill you already take also slow your ageing? Researchers at Northeastern University and Harvard…
1 min
New target cuts clot risk without bleeding danger
Blood clotting is normal and necessary after an injury. But with aging, the system misfires more often, producing dangerous clots.
2 min
Heart valve atlas links birth defects to aging disease
A detailed cell map of the human heart captures how the aortic valve forms, and shows that molecular signatures from embryonic…
2 min
Blocking one protein helps injured kidneys heal
A drug originally developed to help the heart recover after a heart attack may also help kidneys repair themselves after injury.
2 min
AI spots heart scarring behind sudden cardiac death
More than 350,000 people in the US die suddenly from cardiac arrest each year. Many appear healthy beforehand. A new AI model…
1 min
Fat around arteries fuels heart disease from within
A thin layer of fat wraps around most small arteries. In healthy people, it helps vessels relax. In obesity and high blood…
2 min
Immune cells fight tumors by damaging their blood supply
The immune system can attack cancer in a way researchers long overlooked: by damaging the blood vessels that feed a tumor.…
1 min
Progeria research opens new doors to aging and heart disease
A rare disease that makes children age decades too fast is teaching scientists about normal aging. Researchers gathered in…
1 min
Your brain constructs pain from heart rate signals
Your heart speeds up when you expect pain. But what happens if you receive false information about your own heartbeat?
1 min
Senescent cells fuel blood vessel growth in bowel cancer
In bowel cancer, senescent cells in the surrounding tissue help tumours grow new blood vessels. That makes certain tumours…
2 min
Blueberry extract boosts blood vessels and cuts inflammation
An extract from a South American blueberry helps blood vessel cells form new branches. It also dampens one of the most…
2 min
Damaged mitochondria fuel aging inflammation
The chronic low-grade inflammation that comes with old age has long been linked to dementia, heart problems and muscle loss.
2 min
A brain alarm system misfires as we age
In healthy brains, an alarm system stands guard against invaders. In aging brains, that same system fires continuously,…
2 min
Severe obesity reshapes the heart’s muscle proteins
In severe obesity, the heart works differently at the molecular level. A study in Science now shows exactly what changes…
1 min
A tiny RNA molecule shapes immune cells in plaques
Atherosclerosis turns dangerous when immune cells stop doing their job. A small piece of genetic material may decide which way…
1 min
Cholesterol in ear cells determines if you keep hearing
Hearing loss is usually blamed on noise or age. But a new study in eLife points to something far less discussed: the…
1 min
Harvard explains longevity science to everyone
Harvard has published a comprehensive report on living longer, written for ordinary readers. That sounds straightforward. But…
2 min
Cardiovascular Risk Doubles During Perimenopause
Women in perimenopause are twice as likely to have poor cardiovascular health as women who have not yet begun the transition.…
1 min
Cyclarity reports safety data for atherosclerosis drug
A toxic form of cholesterol accumulates in blood vessels and contributes to atherosclerosis.
1 min
Summit reveals tensions in longevity investment
Who is paying for longevity science, and what do they expect in return? At the STAT Breakthrough Summit West, leaders from…
1 min
Organ-specific aging clocks measure each organ separately
Your liver can be ten years older than your heart, while your calendar age gives the same number for both. New aging clocks…
2 min
Cyclarity clears phase 1 trial for 7KC drug
Most treatments for cardiovascular disease work by lowering cholesterol or dampening inflammation. Cyclarity is taking a…
1 min
Repair Bio targets free cholesterol in liver
Cardiovascular disease is the leading cause of death worldwide. Most treatments slow its progression. Repair Biotechnologies…
2 min
Microtubule dynamics direct heart cell growth
Heart muscle cells are elongated for a reason: shape drives function. How cells maintain that shape during growth was poorly…
2 min
Toxic cholesterol cleared via urine in trial
Most cardiovascular therapies lower cholesterol or reduce inflammation. A new clinical result takes a different approach:…
2 min
New therapy targets toxic cholesterol byproduct in arteries
Most cardiovascular treatments lower LDL cholesterol or reduce inflammation. A new drug candidate takes a different approach,…
2 min
Brain vessel vesicles signal cognitive decline
Tiny structures secreted by brain blood vessels may indicate whether someone is heading toward cognitive decline. That is the…
2 min
Sleep apnea ages your blood vessels faster, and researchers now know why
Sleep apnea doesn’t just leave you tired. New research shows it accelerates vascular aging through a specific biological…
2 min
A Compound in Tropical Fruit Relaxes Blood Vessels, Scientists Now Know Exactly How
The rind of the mangosteen, a tropical fruit, contains a compound that widens blood vessels.
2 min
Blood Vessel Walls in Adult Mice Can Still Produce Blood Stem Cells
The textbook account of how adult blood is made has a clean simplicity to it: bone marrow stem cells do the job, period.
2 min
Reprogramming Heart Cells Could Limit the Damage of a Heart Attack
Heart muscle cannot grow back after a heart attack. The dead tissue becomes scar tissue, and that scar gradually undermines…
2 min
Dirty air may be aging your cells faster than the years on your passport
Air pollution has long been linked to heart disease, lung damage, and cancer.
2 min
The beating heart actively suppresses cancer., Scientists have found out why
Cancer cells that reach the heart barely grow at all. Researchers have now discovered that the mechanical force of a beating…
2 min
The beating heart suppresses metastases: a discovery that turns oncology upside down
Tumor cells that reach the heart barely grow at all. Researchers have found that the mechanical load of the beating heart…
2 min
Red Blood Cells Have a Secret Route for Oxygen Transport Under Stress
Your body has a backup plan for when blood cell production falters. Researchers have uncovered an unknown pathway that allows…
2 min
How two aging processes team up to damage blood vessels
Arterial stiffening, high blood pressure, a leaking blood-brain barrier, many of the health problems that come with age begin…
2 min
Brain blood vessels are smarter than we thought; and that opens new doors for treating brain disease
The blood-brain barrier keeps harmful substances out of the brain, but exactly how it works has largely remained a mystery.
2 min
A protein disease almost everyone gets, but doctors rarely catch
Nearly every older person has it in some form: a protein that slowly misfolds and accumulates in the heart and other organs.
2 min
A gene therapy is teaching the heart to repair itself after a heart attack
When a heart attack strikes, heart muscle dies, and it doesn’t grow back.
2 min
Getting a flu shot protects your heart too, not just your lungs
Influenza kills tens of thousands of people every year in the US alone, and many of those deaths aren’t directly from the…
2 min
How heart cells die in old age, and why it causes so much damage
Not all cell death is the same. Some cells go quietly. Others set off a chain reaction that damages surrounding tissue for years.
2 min
Scientists Describe How Cells Die in the Aging Heart
How does a heart cell die? Not always quietly and cleanly. Sometimes a cell enters a kind of emergency state that triggers…
2 min
The bacteria in your mouth may be quietly damaging your brain
We’ve known for years that gum disease is bad for your heart.
2 min
One protein, two heart diseases: could atrial fibrillation and heart failure share the same root cause?
For decades, atrial fibrillation and heart failure have been treated as entirely separate diseases.
2 min
One protein, two heart conditions: could atrial fibrillation and heart failure share the same cause?
Atrial fibrillation and heart failure have been treated as two separate diseases for decades.
2 min
Attacking Atherosclerosis from Within: Immunotherapy Takes Aim at the Most Dangerous Cells in Artery Walls
Arterial plaque is the silent engine behind most heart attacks and strokes.
2 min
Oxidized LDL: The Missing Link Between Cholesterol and Vascular Dementia
LDL cholesterol has long been flagged as a cardiovascular risk factor.
2 min
Oxidized LDL: the silent link between high cholesterol and dementia
LDL cholesterol has been recognized as a risk factor for cardiovascular disease for decades.
2 min
7-Ketocholesterol: The Cholesterol Derivative That Complicates Aging
Cholesterol has a bad reputation, but the real story is far more complex.
1 min
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