A protein involved in cellular transport turns out to limit serious brain damage in mice. And it works across two distinct neurological diseases.
When it comes to diseases like Alzheimer’s and Parkinson’s, attention typically focuses on neurons dying.
Not everyone’s brain ages at the same pace. A single gene variant appears to make neurons more resistant to harm.
Population aging raises dementia rates. But particulate air pollution does too, and possibly more than expected. New research compares the two effects for the first time in a systematic way.
Just two doses of a nasal spray improved memory and cognitive function in aging mice for several months.
Meeting current vitamin B12 guidelines might not be enough to protect the aging brain.
Tuberculosis still kills more than a million people every year. Older adults are far more likely to die from it than younger people.
The same protein accumulates in the brains of patients with more than twenty different diseases.
Every bacterium in your body constantly sends out tiny molecular packages. A new hypothesis proposes that the build-up of these packages in the brain contributes to neurodegenerative disease.
Neurons must survive for decades without dividing. That makes DNA repair critical — and a new study shows one key repair protein loses its footing with age.
When neurons die, they do not simply stop working. They send out signals that damage surrounding healthy cells. Researcher Chaska Walton is developing a targeted delivery system to interrupt that process.
In ALS and a form of frontotemporal dementia, a protein called TDP-43 clumps together in nerve cells — and kills them.
By the time someone forgets a name or gets lost on a familiar route, Alzheimer’s disease may have been quietly progressing in their brain for twenty or thirty years.
Your brain has a built-in system for clearing out damaged proteins. As we age, that system becomes increasingly impaired — and researchers have now identified a likely culprit: oxidative stress disables the…
A worm barely a millimeter long can sniff out bacteria enriched with a specific amino acid it cannot make itself.
A small molecule that blocks a key inflammation trigger in the brain has cleared its first human trial without serious side effects.
Tau protein is present in almost every brain over the age of eighty, yet most people never develop dementia.
The gut microbiome sends a constant stream of chemical signals to the brain. In people with Alzheimer’s or Parkinson’s disease, that microbial community looks systematically different — and researchers are now asking…