What if you could test how a cell responds to a genetic intervention before running a single experiment?
There is a molecular brake on your DNA repair system. The more active that brake, the faster cells accumulate errors — and the faster you age.
Cells have ways to permanently silence certain genes. One of those guardians is the protein MORC2.
A small chemical tag on an amino acid turns out to play a surprisingly large role in cell biology.
European health data sits locked in national systems. A new proposal in Science argues for a different approach: instead of sharing patient data, share the AI models trained on it.
People in excellent physical condition score almost identically to sedentary peers on most mainstream epigenetic aging clocks. That reveals a fundamental limitation in how these tools are built.
Inject genetic code into cells, then switch it on from outside the body using an electromagnetic device. It sounds like science fiction.
Imagine a trial on a dietary intervention finding that participants become biologically younger.
Spatial transcriptomics — the technology that maps which genes are active where inside a tissue — is one of the most exciting tools in aging research.
One of the twentieth century’s most devastating epidemics may have done something extraordinary: triggered a measurable evolutionary shift in human populations within just a few decades.
Kangaroos independently evolved thick tooth enamel, just like several other large mammals did before them.
Your DNA doesn’t change, but the way your genes are read does. A new review in Science maps how epigenetic changes — driven by diet, stress, and environment — shape long-term health…
Every cell in your body carries nearly identical DNA, yet a liver cell and a brain cell look and behave completely differently.
Two of the most discussed processes in aging science — chronic low-grade inflammation and epigenetic changes in DNA — turn out to be closely connected.
Scientists studying how genes drive aging have long faced a frustrating problem: the tools to switch genes on and off in living animals work, but not cleanly enough.
Ten thousand years ago, humans started growing crops and raising animals. That shift didn’t just change dinner — it accelerated our biological evolution in ways scientists are only now beginning to fully…
When mice are trained to fear a specific odor, the structure of their offspring’s smell system changes — even though those offspring never encountered the scent themselves.
Nearly half of the human genome consists of remnants from ancient viral infections. In youth, cells keep these sequences locked down. As we age, the locks weaken.
A fragment of a protein that normally helps organise the cell’s genetic material can create small, temporary gaps in DNA — and those gaps, counterintuitively, appear to trigger repair processes that roll…
Every cell contains millions of proteins that must be in exactly the right place at the right time.
Life Biosciences is about to become the first company to test a therapy that makes cells biologically younger — not as a treatment for a specific disease, but for aging itself.
The FDA doesn’t officially recognise aging as a disease. Yet this year, for the first time, a therapy designed to make cells biologically younger is entering human trials.
A small biotech company is about to test whether ageing cells can literally be ‘rewound’ in living humans. If it works in the eye, it could change medicine forever.
Nearly half the human genome consists of ancient ‘parasitic’ DNA — sequences that once copied and pasted themselves throughout our chromosomes. In healthy cells they are silenced.
Brief exposure to Yamanaka factors can reset cells epigenetically toward a younger state. In mice, the results are striking.