A gene that barely registers outside research labs turns out to significantly extend the lifespan of fruit flies. And it does so by improving how mitochondria work.
Eating within a fixed daily window improves health in both male and female mice. But only males actually live longer because of it.
A little-known protein has been shown to extend the lifespan of fruit flies by improving how their cells produce energy.
The cells that make eggs and sperm do more than enable reproduction. They also send signals that control how fast the rest of the body ages.
Organs do not age in isolation. As kidney function drops, the rest of the body follows. New research maps how renal decline and physical frailty reinforce each other in older adults.
Scientists keep producing new tools to measure biological aging. The latest uses amino acid levels in blood. But does it actually tell us anything new?
There is a molecular brake on your DNA repair system. The more active that brake, the faster cells accumulate errors — and the faster you age.
The idea is straightforward: a body that has endured years of stress is more worn down than one that hasn’t.
A new material can measure electrochemical signals from living tissue while stretching with the skin or muscle beneath it. That solves a long-standing problem for wearable and implantable health sensors.
A single biological measurement tells you one piece of the aging story. Researchers now argue that combining multiple layers of data into one clock produces far more reliable results.
A protein best known from cancer research turns out to play a key role in brain aging.
Men and women do not age the same way. The immune system follows different decline trajectories in each sex.
A scan of the retina can reveal more than eye health. New research shows that an aging clock based on retinal images correlates with the progression of bone loss (osteoporosis) in older…
Your liver can be ten years older than your heart, while your calendar age gives the same number for both. New aging clocks now make that difference visible.
A single blood test that reveals your biological age rather than your calendar age. That is the promise of proteomic aging clocks.
A single brain scan and an algorithm. That combination may be enough to predict whether someone will develop Alzheimer’s, how fast their cognition will decline, and how severe the diagnosis will be…
Measuring tissue aging usually requires a biopsy or imaging scan. A newly developed probe could make it as simple as collecting urine after a single injection.
Detecting the buildup of aging cells in the body has always required invasive tissue samples. A new study suggests a simple urine test could do the job instead.
Scientists studying aging face one persistent obstacle: it takes a long time for animals to grow old. An unlikely solution is gaining serious attention — microgravity.
Something fundamental shifts in your gut as you age, and that shift makes it easier for dangerous bacteria to take hold. Researchers have now mapped out the mechanism in unusual detail.
Millions of older adults take daytime naps and feel better for it. But a new study links longer and more frequent napping to a higher risk of death.
People living at high altitude have less oxygen available. That has a surprising consequence: their immune systems appear biologically older than those of people at sea level — even when they seem…
In most mammals, the community of bacteria living in the gut shifts dramatically with age.
Air pollution has long been linked to heart disease, lung damage, and cancer. But researchers are now asking a sharper question: does breathing polluted air actually make the body biologically older, faster…
A gene associated with longer lifespan in fruit flies for decades appears to work partly through the animal’s gut bacteria.
Ribosomes are the molecular machines inside every cell that build proteins. They were long thought to work identically in everyone.
Your body can be biologically older or younger than your birth certificate suggests — and a type of inflammation you never feel may be quietly pushing that number up.
The immune systems of men and women don’t just age at different rates. They age along fundamentally different trajectories — with real consequences for who gets sick, when, and from what.
Nearly half of the human genome consists of remnants from ancient viral infections. In youth, cells keep these sequences locked down. As we age, the locks weaken.
Older people don’t die from the flu more often simply because they’re frail. They die because their immune system can produce fewer new defenders each year while simultaneously staying locked in a…
You could follow the most nutritious diet imaginable — but if your first meal comes late in the day and your last one lands close to midnight, your body may still be…
Life Biosciences is about to become the first company to test a therapy that makes cells biologically younger — not as a treatment for a specific disease, but for aging itself.
Immunity doesn’t age the same way in everyone. A new study of nearly a thousand people reveals that women and men follow fundamentally different immune aging trajectories — with far greater cellular…
A biotech company has received FDA clearance to begin resetting the biological clock in human eye tissue.
Same species, same lifespan pressures — but the immune system ages in strikingly different ways depending on whether you’re female or male.
You could follow every dietary guideline perfectly, but if you’re eating dinner at 10 pm, your cells may be aging faster regardless.
Mitochondria have their own DNA, and errors in it accumulate as we age.
A small biotech company is about to test whether ageing cells can literally be ‘rewound’ in living humans. If it works in the eye, it could change medicine forever.
Mitochondria — the energy generators inside our cells — carry their own DNA, separate from the cell’s nucleus.
A blood test that can detect Alzheimer’s disease years before symptoms appear sounds like unambiguous progress.
Patients are arriving at clinics clutching reports of their ‘biological age’ — a number generated from a cheek swab or dried blood spot mailed from home. The appeal is obvious.
A small organ tucked behind the breastbone, largely ignored after childhood, turns out to be one of the more powerful predictors of mortality.
A small organ tucked behind the breastbone, largely ignored after childhood, turns out to be one of the more powerful predictors of mortality.
Patients are arriving at clinics clutching reports of their ‘biological age’ — a number generated from a cheek swab or dried blood spot mailed from home. The appeal is obvious.