Exercise damages your cells. But that damage is precisely what makes you healthier. A protein called HMGB1 appears to be the key to that paradox.
The standard advice of 150 minutes of exercise per week may be seriously undershooting the mark.
Exercise improves metabolism in dozens of ways, but pinpointing which molecule causes which benefit is genuinely hard.
People in excellent physical condition score almost identically to sedentary peers on most mainstream epigenetic aging clocks. That reveals a fundamental limitation in how these tools are built.
Scientists studying aging face one persistent obstacle: it takes a long time for animals to grow old. An unlikely solution is gaining serious attention — microgravity.
A compound from traditional herbal medicine activates pathways in mice that closely resemble the biological effects of physical exercise. But the gap between mouse data and human benefit remains wide.
Exercise is the best-supported intervention against aging. But what if a plant compound could activate the same signals inside cells?
Astronauts returning from space look as though they have aged by years. That is not coincidence.
Creatine is usually thought of as a supplement for young athletes. But a new study suggests its real potential may lie in older adults — when combined with a specific type of…
Older adults who exercise regularly have measurably different gut bacteria than those who don’t.
Rapamycin is widely considered the leading drug candidate for slowing aging — but a new study suggests it may undercut the health gains from physical exercise in older adults.
Everyone knows that fit people live longer and get sick less often. But proving that exercise actually causes that better health — rather than the other way around — turns out to…
Sitting still in intense heat turns out to do something the body normally reserves for physical exertion.
A single half-hour sauna session is enough to temporarily spike the number of white blood cells circulating in the body.
King penguins moved from the wild to a zoo get all the food they want and never have to work for it.