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Answers to the questions you ask yourself about healthy aging.

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InterventionsRapamycin, metformin, GLP-1 and other widely-discussed compounds.
  • What are the effects of microdosing with Ozempic?
  • Does strength training work as well as medication for osteoporosis?
  • Do ketone drinks do anything for your brain or performance?
266 answers · 1,678 studies
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MetabolismBlood sugar, insulin and weight , the engine of aging.
  • What are the effects of microdosing with Ozempic?
  • What do mitochondrial mutations mean for how quickly you age?
  • Does a fasting-mimicking diet work better than simply eating less?
119 answers · 781 studies
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Heart & vesselsCholesterol, blood pressure and vascular age , the biggest cause of death.
  • How much does ultra-processed food increase your risk of dying?
  • Is your oral health linked to cardiovascular disease?
  • How many sauna sessions per week produce health benefits?
101 answers · 642 studies
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SleepHow much sleep you need and what poor sleep does.
  • Are sleep trackers accurate enough to help you improve your sleep?
  • How much melatonin should you take to sleep better?
  • Does the sleepy girl mocktail (magnesium with cherry juice) help you sleep?
81 answers · 503 studies
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HormonesTestosterone, menopause and hormone therapy as you age.
  • Why do bones become more brittle after menopause, and what can help?
  • What can help women increase their libido?
  • Do your hormones influence how quickly you age?
80 answers · 537 studies
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Immune systemInflammation, defence and how your immune system ages.
  • What is the role of chronic inflammation in the development of cancer?
  • How harmful are microplastics in your body to your health?
  • Is raw milk healthier than pasteurised milk?
73 answers · 489 studies
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SkinSkin aging and what actually helps against it.
  • Does omega-3 protect your skin from sunburn?
  • Does slugging (smearing your skin with petroleum jelly) actually work?
  • Does skin cycling really work better for your skin?
72 answers · 443 studies
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CancerScreening, lifestyle and what shapes your cancer risk.
  • Does linoleic acid in tissue increase the risk of skin cancer?
  • What is the role of chronic inflammation in the development of cancer?
  • Which cancer screenings are worthwhile, and from what age?
68 answers · 444 studies
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Gut & microbiomeGut flora, fibre and fermented foods.
  • Can you permanently change your gut microbiome through diet?
  • How much probiotic do you need per day?
  • Can probiotics improve your health in later life?
66 answers · 425 studies
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Aging clocksBiological age, epigenetic clocks and biomarkers of aging.
  • Does your telomere length tell you anything useful about your health?
  • Do epigenetic clocks differ so much that your result is essentially random?
  • Can epigenetic reprogramming reverse ageing?
65 answers · 395 studies
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Cells & DNATelomeres, mitochondria, senescence and NAD , aging at the cellular level.
  • What do mitochondrial mutations mean for how quickly you age?
  • Can you repair DNA damage, or can you only prevent it?
  • What exactly does senescence do to your cells as you age?
65 answers · 443 studies
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BonesBone density, osteoporosis and strong bones in later life.
  • Why do bones become more brittle after menopause, and what can help?
  • What does a DEXA scan tell you that a regular bone density measurement does not?
  • Does strength training work as well as medication for osteoporosis?
64 answers · 423 studies
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